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Circadien cycle and chronic central serous chorioretinopathy
Author(s) -
HUBAULT B,
SETROUK E,
ZAMBROWSKI O,
DUCASSE A,
ARNDT C
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.4226.x
Subject(s) - medicine , corticosteroid , serous fluid , visual acuity , circadian rhythm , pediatrics , ophthalmology , surgery
Purpose Chronic central serous chorioretinopathy (CSCR) is a multifactorial disease. The present study was designed to evaluate the prevalence of circadian disturbance and corticosteroid treatment in patients treated with chronic CSCR. Methods Patients presenting with chronic CSCR between 01/01/2009 and 30/11/2011 were prospectively enrolled. A history of corticosteroid treatment, sleep disturbances and irregular working hours was noted. Two questionnaires (PSQI and Epworth) regarding sleeping distrurbancies were applied. After a follow up of 3 months, the patients with persisting fluid and visual acuity below 20/40 were treated with photodynamic therapy (PDT). Results During the period of inclusion, among 26 included patients, 19 were treated with PDT (73%). A history of corticosteroid tretment was found in 12 patients (19%), 4 currently used psychopharmacologic drugs (15%) and 8 had irregular working hours (30%). The analysis of the Epworth questionnaire enabled to record moderate sleeping disturbances in 11 patients (42%), none of the patients were classified as having severe sleeping disturbances. Conclusion It is likely that general factors such as the existence of a corticosteroid treatment or a disruption of the circadian cycle are involved in the occurrence of patients with CSCR.