Progressive serpiginous choroidopathy – what to do?

A 52 year‐old Caucasian female, diagnosed at the age of 11 with tuberculosis presented years later with a picture of serpiginous choroidopathy initially affecting one eye, but later both. She lost vision in her right eye as a consequence of a CNV. She received three courses of anti‐TBc treatment but the disease continue to progress. Conventional immunosuppressive therapy was also added with minimal impact on recurrences. Currently in the process of receiving anti‐TNF therapy. Infection versus immune response, or a bit of both?