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Macular sensitivity and structure in epiretinal membranes 6 months after surgical treatment
Author(s) -
CREUZOT C,
ISAICO R,
NICOT F,
BRON A
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.3823.x
Subject(s) - microperimetry , medicine , visual acuity , optical coherence tomography , epiretinal membrane , ophthalmology , prospective cohort study , internal limiting membrane , pro re nata , external limiting membrane , surgery , vitrectomy , retinal , macular hole , ranibizumab , bevacizumab , chemotherapy , retinal pigment epithelium
Purpose To evaluate the evolution of macular sensitivity (MS) and its correlation with visual acuity (VA) and Spectral‐Domain Optical Coherence Tomography (SD‐OCT) in patients with idiopathic epiretinal membrane (ERM) at 3 and 6 months after surgical treatment. Methods In this prospective, monocenter, interventional case series, we included 49 patients (49 eyes) with an idiopathic ERM scheduled for a surgical treatment. Among these patients, 34 were evaluated at 3 months (M3) and 32 at 6 months (M6) after ERM and internal limiting membrane removal. At each visit a measurement of ETDRS best‐corrected visual acuity, microperimetry and SD‐OCT were performed for all patients. Results The MS was improved significantly from 11.7±2.1 dB preoperatively to 12.9±1.8 dB (p=0.001) and 13.3±1.9 dB (p=0.001) at M3 and M6 postop respectively. In the same time we observed an improvement of VA from 70.0±10.2 letters ETDRS at inclusion to 80.1±6.9 letters at M3 (p<0.0001) and 80.8±6.5 letters at M6 (p<0.0001). Macular thickness decreased significantly from 412.6±53.1 µm to 340.5±29.6 µm and 332.9±26.9 µm at M3 and M6 respectively. We found a significant correlation between pre and post operative MS at M3 (r=0.565; p=0.0002) and M6 (r=0.584; p=0.0001). A significant correlation between pre and post operative VA was also found at M6 (r=0.558; p=0.0003) but not at M3 (r=0.229; p=0.097). We did not find any significant correlation between the increase in MS and VA (r=0.286; p=0.112) and between MS improvement and macular thickness decrease (r=‐0.196; p=0.283). Conclusion Complementary aspects of macular function were given by VA and MS measurements after ERM surgery.