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Biofilms in ocular infection
Author(s) -
SHANKS RM,
ROMANOWSKI E,
KOWALSKI R
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.3443.x
Subject(s) - biofilm , medicine , osteomyelitis , cystic fibrosis , otitis , microbiology and biotechnology , biology , bacteria , immunology , surgery , genetics
Purpose To discuss the evidence for microbial biofilms in ocular infections. Methods A description microbial biofilms and a review of the evidence in the literature for bacterial biofilms in ocular infections. Results Microbial biofilms are surface attached communities of microbes that are recalcitrant to antibiotic therapy and associated with a wide number of human diseases including, but not limited to as cystic fibrosis, dental caries, otitis media, osteomyelitis, and chronic wounds. There is an increasing body of evidence supporting the potential role of microbial biofilms in ocular infections. Conclusion The model that biofilms contribute to ocular infections is an exciting new arena of study.