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The Project of “Virus‐induced anterior Uveitis”
Author(s) -
ZIERHUT M
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.4446.x
Subject(s) - medicine , uveitis , cytomegalovirus , anterior uveitis , herpes simplex virus , ophthalmology , varicella zoster virus , glaucoma , dermatology , virus , immunology , herpesviridae , viral disease
Purpose To summarize the clinical signs of virus‐induced anterior uveitis and to compare our understanding with the results of a Symposium recently hold in Berlin, comparing proven to unproven cases of herpes simplex virus (HSV), varicella‐zoster virus (VZV), cytomegalovirus (clinically like Posner‐Schlosman Syndrome), and rubella virus (clinically the picture of Fuchs heterochromic uveitis). Methods Presentation of typical signs and symptoms of anterior uveitis which may be viral induced. This will include secondary glaucoma, keratitis, iris color changes, synechiae, complications like cataract and macular edema. Results Typically viral induced anterior uveitis only sometimes leads to posterior synechiae (HSV, VZV), mostly to a mild anterior chamber inflammation, and very rarely to macular edema Conclusion We plan a worldwide prospective trial for reaching more information about the role of virus in anterior uveitis, with tap of the anterior chamber and evaluation of the antigen and the antibody response.