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Correlation between exudative age‐related macular degeneration and pseudoexfoliation syndrome
Author(s) -
SIRTAUTIENE R,
ASOKLIS R,
LIUTVINAITE R,
BABRAUSKAITE E
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.351.x
Subject(s) - medicine , macular degeneration , ophthalmology , exudative age related macular degeneration , pseudoexfoliation syndrome , correlation , glaucoma , geometry , mathematics
Purpose To evaluate the correlation between exudative age related macular degeneration (AMD) and pseudoexfoliation syndrome (PEX) in patients receiving Bevacizumab therapy for AMD. Methods Consecutive 200 patients with exudative AMD treated with Bevacizumab at Vilnius University Hospital between December 2010 and March 2011 were included into the study. Each patient’s data was recorded only once. Those with retinal occlusive disease were excluded. The results were statistically analysed by SPSS 19.0 program. Results 135 (67.5%) females and 65 (32.5%) males were studied. The mean age was 73.9 (SD=0.6) years. The difference between the mean age of female and male patients was statistically not different (74 and 73.3 years respectively). The prevalence of PEX in the treated as well as in the controlateral eye was 15.5% (31 patients), binocular PEX was in 32% of the eyes, in all there were 15.0% eyes with PEX. There was no statistically significant correlation between the type of AMD and frequency of PEX, but the frequency of PEX in eyes with AMD was twice larger than in controlateral eyes without AMD: Odds ratio was 1.96 (95% CI: 0.4‐8.6). No correlation was found between sex, AMD type and PEX. Conclusion In our study exudative AMD was found more often in female patients. PEX was found more often in eyes with AMD. No statistically significant differences between frequency of PEX and type of AMD were found. Further studies are necessary to achieve statistically significant results.