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The effect of intravitreal ranibizumab on retinal oxygenation in central retinal vein occlusion
Author(s) -
TRAUSTASON S,
LA COUR M,
LARSEN M
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.3424.x
Subject(s) - retinal , medicine , ophthalmology , ranibizumab , central retinal vein occlusion , retinal vein , visual acuity , surgery , bevacizumab , macular edema , chemotherapy
Purpose To investigate the effect of intravitreal anti‐VEGF on retinal oxygenation in patients with central retinal vein occlusion. Intravitreal anti‐VEGF injections have recently become an approved method of treatment for retinal vein occlusions, as several studies have shown a beneficial effect on visual acuity and retinal thickness. However, there are indications that intravitreal anti‐VEGF may cause constrictions of the retinal vessels, leading to a reduction in retinal blood flow. Methods Retinal oxygen saturation in patients with CRVO was analysed, using the Oxymap Retinal Oximeter P3, before and during 6 months of treatment with intravitreal injections of ranibizumab. Results Our preliminary results indicate that retinal oxygen saturation is not decreased by intravitreal anti‐VEGF injections.Commercial interest