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Amniotic membrane transplantation
Author(s) -
LANZINI M,
CALIENNO R,
CURCIO C,
CIAFRè M,
COLASANTE M,
NUBILE M,
MASTROPASQUA L
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.3274.x
Subject(s) - cornea , transplantation , medicine , perforation , amnion , corneal transplantation , corneal diseases , in vivo , pathology , corneal perforation , ophthalmology , surgery , biology , materials science , pregnancy , fetus , genetics , microbiology and biotechnology , metallurgy , punching
Purpose Aim of this presentation is to indicate current applications of amniotic membrane transplantation in corneal diseases and to describe, by means of in vivo imaging techniques, postoperative modifications of corneal tissue. Methods Different indications for Amniotic Membrane Transplantation will be presented as clinical cases and literature review including corneal ulcers and perforations, persistent epithelial defect, bullous keratopathy. Surgical techniques and adverse events will be described and morphological changes of transplanted tissue and corneal profile will be analyzes by means of anterior segment OCT and in vivo confocal microscopy. Results Amniotic membrane transplantation allows to obtain epithelial restoring, corneal sealing and stromal thickness recovery together with an antinflammatory effect on corneal tissue and reduction of pain. Transplanted tissue may be differently oriented and composed to obtain different effects on recipient cornea. Conclusion Amniotic membrane transplantation is an useful surgical technique for managing of ulcerative corneal pathologies with or without perforation and epithelial defects. In vivo imaging diagnostic devices enable to visualize postoperative effects of transplanted tissue on recipient cornea in terms of morphology and tissutal modifications.