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Relationship between optical coherence tomography and visual evoked potentials in patients with parasellar tumors without chiasmal compression
Author(s) -
WASIK M,
PILECKI W
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.309.x
Subject(s) - medicine , nerve fiber layer , retinal , ophthalmology , optical coherence tomography , optic chiasm , visual evoked potentials , optic nerve , nuclear medicine , audiology
Purpose To evaluate the relationship between retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (OCT) and visual evoked potentials (VEP) in patients with parasellar tumors without chiasmal compression on MRI examination. Methods 32 eyes of 16 patients suffering from tumor of sella turcica without any chiasmal compression were included to the study and compared to 59 eyes of 30 healthy patients. Exclusion criteria were any other ophthalmic or general condition that can affect both VEP and OCT measurements. All patients underwent MRI of the head to confirm the diagnosis, retinal nerve fiber thickness measurements with OCT and visual evoked potentials. Results VEP of patients with parasellar tumors without any chiasmal compression showed no P100 latency prolongation (OD=101,9 ± 6,3ms, OS= 101,2 ± 6,3 ms) in comparison to control group (102,1 ± 4,5ms and 102,5 ± 4,2ms). There was noticed a reduced P100 amplitude in examined patients (OD=10,9 ± 4,8µV, OS=11,6 ± 5,6µV) comparing to healthy subjects (12,3±6,5 µV and 12,1±6,3 µV respectively), however it was not statistically significant (p=0,5 and p=0,8 respectively). Average RNFL thickness in our patients was lower (OD=102,2±8,9µm, OS=101,8 ± 11,5µm) than in control group (104,7 ± 10µm and 104,5 ± 15µm respectively), but the difference was not statistically significant (p=0,8 and p=0,95 respectively). Conclusion In patients with parasellar tumors without any chiasmal compression both visual evoked potentials and RNFL thickness measurements in OCT showed no significant differences in comparison to healthy subjects.