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The modern management of ocular surface burns
Author(s) -
GICQUEL JJ
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.2471.x
Subject(s) - medicine , transplantation , limbal stem cell , corneal epithelium , surgery , cornea , pterygium , ophthalmology
Ocular surface burns can be due to the exposition to chemical agents, extreme temperatures or ultraviolet, infrared or ionising radiations. Alkali burns differ from acid burns by the fact that they deeply penetrate in the anterior segment and so are particularly severe. Initial clinical examination (with the help of classifications) tells us how to adapt the treatment and gives us the prognosis. The 4 Grades Ropper‐Hall’s classification has been replaced by the more precise 6 Grades Dua’s one. Surgical treatment aiming to restoring a proper corneal epithelium has improved the prognosis of severe cases. It can address the acute (Amniotic Membrane Transplantation, Sequential Sectorial Epitheliectomies) or the late stage of the disease (Limbal Stem Cell (LSC) Transplantation / in or ex vivo expansion). In all cases, an optimal control of the ocular surface inflammation is essential to the LSC survival.