Premium
Ocular temperature rise and light scattering development in the lens correlating with exposure time after in vivo exposure to 1090 nm infrared radiation
Author(s) -
YU Z,
SCHULMEISTER K,
GALICHANIN K,
SÖDERBERG P
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.2362.x
Subject(s) - cornea , in vivo , ophthalmology , lens (geology) , optics , radiation , light scattering , medicine , irradiation , opacity , scattering , materials science , biology , physics , microbiology and biotechnology , nuclear physics
Abstract Purpose To investigate the relationship between light scattering development in the lens and ocular temperature rise after in vivo exposure to high intensity 1090 nm radiation with exposure time up to 60 minutes. Methods 80 six‐weeks‐old albino SD rats were anesthetized and the pupils were bilaterally dilated prior to exposure. The animals were randomly divided into four groups of 20 each. All animals were unilaterally exposed to 3.0 W coherent infrared radiation at 1090 nm with a spot size of 2 mm within the pupil for 10, 18, 33, 60 minutes respectively. During exposure, temperature was recorded at the limbus of exposed eye.7 days after the exposure and both lenses were extracted for light scattering measurements and macroscopic photographing. Results The maximum temperature increase for exposure time of 10, 18, 33, 60 minutes was 7.0, 6.8, 7.6, 7.4 ºC at the limbus of exposed eye. 7 days after the exposure, in all the groups there was no statistical difference of light scattering in the lenses between exposed and non‐exposed contralateral eyes and no significant lens opacities from the exposed eyes were observed. Conclusion An irradiance of 96 W/cm2 of 1090 nm projected on the cornea in vivo induces a constant temperature increase of about 7 ºCin the anterior segment of the eye. At a temperature increase of 7ºC in the anterior segment, no light scattering development and opacity formation in the lens occurs one week after exposure, indicating that there is no direct either photochemical or thermal effect in the lens under the conditions of the irradiance less than 96 W/cm2 on the cornea and temperature rise below 7ºC in the anterior segment for at least 1 hour.