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Long‐term results of simultaneous topo‐guided photorefractive keratectomy followed by corneal collagen cross‐linking for keratoconus
Author(s) -
DIAKONIS V,
GRENTZELOS M,
PORTALIOU D,
KOUNIS G,
LIMNOPOULOU A,
KYMIONIS G
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.2177.x
Subject(s) - keratoconus , corneal collagen cross linking , keratometer , photorefractive keratectomy , dioptre , medicine , ophthalmology , phototherapeutic keratectomy , corneal epithelium , visual acuity , prospective cohort study , cornea , surgery
Purpose To present the long‐term results after simultaneous photorefractive keratectomy (PRK) followed by corneal collagen cross linking (CXL) for keratoconus Methods In this prospective case series, 26 patients (31 eyes) with progressive keratoconus were included. All patients underwent customized topography guided photorefractive keratectomy (PRK) immediately followed by corneal collagen cross linking with the use of riboflavin and ultraviolet‐A irradiation. Epithelium was removed by transepithelial phototherapeutic keratectomy (t‐PTK) in all cases Results Mean follow‐up was 19.53 +/‐ 3.97 months (range 12 to 25 months). Mean preoperative spherical equivalent (SE) was –2.3 +/‐ 2.8 diopters (D) while at the last follow up examination was significantly (p<0.001) reduced to ‐1.08 +/‐ 2.41 D. LogMAR uncorrected (UDVA) and corrected distance visual acuity (CDVA) were significantly reduced by 0.46 and 0.084 LogMAR units, (p<0.001) at the last follow up examination. Mean steep and flat keratometry readings were reduced by 2.35 D (p<0.001) and 1.18 D (p=0.013) at the last follow‐up examination Conclusion Simultaneous topo‐guided PRK followed by CXL seems to be an effective and safe treatment without any complications in our series of keratoconic patients