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A hypothesis about structural changes of the posterior pole based on scleral deformation during ocular movements
Author(s) -
THEOCHARIS IP
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2011.2135.x
Subject(s) - posterior pole , sclera , macular degeneration , medicine , serous fluid , ophthalmology , anatomy , visual acuity , pathology
Purpose To propose a theoretical model of the pathogenesis of various macular diseases based on structural deformation of the stratified posterior pole during ocular movements Methods CT, MRI and OCT scans show evidence of significant deformation of the posterior sclera wall during ocular movements.The posterior pole is seen as a stratified model of multiple layers with different elastic properties.The morphology of lessions of various macular diseases is examined as a consequence of the compression of the stratified posterior pole using basic principles of mechanics. Results The clinical expression of various macular diseases such as age‐related macular degeneration, macular hole, central serous choroidopathy could be explained by a unifying mechanism of structural changes that includes the role of the choroidal bed as a dampening stroma. Conclusion The structural behavior of the multilayered stratified posterior pole during ocular movements may open a new field of research and treatment of the posterior pole diseases.