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Choroidal thickness measurement in highly myopic eyes using SD ‐ OCT
Author(s) -
EL MATRI L,
BOULADI M,
CHEBIL A,
KORT F,
TRIKI M,
LIMAIEM R,
MGHAIETH F
Publication year - 2010
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2010.4319.x
Subject(s) - choroid , dioptre , ophthalmology , medicine , choroidal neovascularization , retinal pigment epithelium , optical coherence tomography , refractive error , retinal , retina , visual acuity , optics , physics
Purpose to measure macular choroidal thickness (CT) using spectral domain optical coherence tomography (OCT) and to investigate the correlation between CT and age, degree of myopia, and a history of macular choroidal neovascularization (CNV). Methods a cross sectional study was performed in 191 eyes of 106 patients with spherical equivalent (SE) refractive error of 6 diopters (D) or more, between early January 2010 and early June 2010. The choroid was imaged using the spectral domain OCT (OCT TOPCON 2000) by changing the reference position from the vitreous to the choroid without inverting the image. CT was measured from the outer border of the hyperreflective line corresponding to the retinal pigment epithelium (RPE) to the inner scleral border. Results the mean age of the 106 patients was 47,9 years ( ± 14,89 years; range, 18 to 81 years), 32 were men and 74 were women, the mean SE refractive error was 13,73 D (±5,74 D), and the mean subfoveal CT was 100,42 µm (±60,15µm; range, 23‐278). CT was correlated negatively with age (p= 0,01), and refractive error (p=0,01). Fourty eyes had a history of CNV, the mean CT was 52,02 ± 17,65 µm, and this was significantly thinner than the subgroup without CNV (p<0,10‐6 ). Conclusion in highly myopic eyes, the choroid is thin and undergoes further attenuation with increasing age and increasing myopia. In addition, these findings suggest that the choroid may play a role in the pathogenesis of choroidal neovascularization.