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Intravitreal bevacizumab for macular telangiectasia
Author(s) -
LIBONDI T,
VON BALTZ S,
JONAS JB
Publication year - 2010
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2010.4312.x
Subject(s) - medicine , visual acuity , macular telangiectasia , ophthalmology , fluorescein angiography , retinal , bevacizumab , telangiectasia , macular edema , surgery , chemotherapy
Purpose Idiopathic macular telangiectasia Type 2 (idiopathic perifoveolar telangiectasia, ITP) is an uncommon, slowly progressive, usually bilateral disease of the macula, characterized by dilated, tortuous capillaries in the perifoveolar region, preferably in the temporal part. It is the scope of our study to report about a 36 month follow‐up of patients affected by ITP and treated with multiple intravitreal injection of bevacizumab Methods Our retrospective, interventional study included 8 eyes of 8 patients, 4 of whom were male, affected by IPT and treated with multiple intravitreal injections of 1,25 mg. bevacizumab, whose maximum follow‐up extended to 36 months (range 3‐36 months). Age ranged from 37 to 83 yo.They underwent a complete ophthalmic examination including best corrected visual acuity (BCVA) testing, slit lamp examination with indirect ophtalmoscopy, fluorescein angiography and time‐domain OCT (Status OCT Carl Zeiss Meditec, ver. 4.01). All the diagnosis were made by a single examiner based on the unique features of the disease Results The injection provided a time‐limited positive effect on both visual acuity and OCT central thickness (1 month). It was only slightly effective on both parameters if we consider the 6th month follow‐up, while at 24 month follow‐up the considered parameters did not show any significant difference from the baseline. Conclusion Our results show a limited benefit on visual acuity and retinal edema in the short follow‐up. While not demonstrating a positive therapeutical effect in the long term, they seem to point out to a time‐limited positive effect on retinal edema.