Premium
Neural contrast sensitivity calculated from measured total contrast sensitivity and modulation transfer function
Author(s) -
MICHAEL R,
GUEVARA O,
BARRAQUER RI
Publication year - 2010
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2010.3323.x
Subject(s) - keratoconus , contrast (vision) , ophthalmology , retina , retinopathy , medicine , diabetic retinopathy , cornea , optics , diabetes mellitus , endocrinology , physics
Purpose To test the feasibility of calculating neural contrast sensitivity function (neural CSF) from conventionally measured total contrast sensitivity function (total CSF) and measured modulation transfer function (MTF). Neural CSF considers the retina and the brain, whereas total CSF considers the optical eye media, the retina and the brain together. Methods Three groups with 9 eyes each, one group with normal ocular optics but with retinal alterations (mild diabetic retinopathy), another with altered ocular optics and normal retina (keratoconus) and a normal control group were studied. Results Total CSF in the keratoconus and retinopathy group was significantly lower as compared with the control group. MTF for keratoconus was lower and in the retinopathy group was similar to the control group. Calculated neural CSF in the diabetes mellitus group was lower than in the control group whereas in the keratoconus group it was similar to the control group, with overestimations for some keratoconus cases. Conclusion It is possible to calculate a meaningful neural CSF from measured total CSF and MTF data. The neural CSF represents a CSF adjusted for optical aberrations. This would allow comparing the neural component of visual function in eyes with different optical aberrations.