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The range of waveform score of Ocular Response AnalyzerTM (ORA) in healthy subjects: interim analysis
Author(s) -
VANTOMME M,
MOUSTAKA L,
POURJAVAN S
Publication year - 2010
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2010.2354.x
Subject(s) - waveform , medicine , ophthalmology , spearman's rank correlation coefficient , signal (programming language) , statistics , mathematics , physics , computer science , quantum mechanics , voltage , programming language
Purpose To assess the range of waveform score in IOP measurements with ocular response analyzer (ORA, Reichert) in healthy subjects. Methods Prospective study including both eyes of healthy subjects with no ocular pathology or previous refractive surgery. The IOP measurements with ORA from both eyes were performed. The inclusion criteria of the measurements were solely based on good waveforms by an experienced clinician. The waveform score of three measurements were included for statistical analysis. Other parameters including age, central corneal thickness (CCT) and axis length were also analysed to evaluate possible correlations. Spearman correlation coefficient was used to assess the correlation. Results To date, both eyes of 42 healthy subjects are included (Mean age: 46.6 ± 14.3 yrs, Axial length: 23.7 ± 1.1, CCT: 554 ± 34 µm). The mean waveform scores from the first IOP measurement were 4.2±2.3 and for the 2de and 3th respectively 4.2±1.9 and 4.2±2.1 (not significantly different). The mean waveform score of 252 signals (both eyes and 3 measurements) was 4.2±2.1 and ranged from 0.3 to 9.6. Considering the best signal value per patient, the mean of all best signal values was 5.5±2.0 and it ranged from 1.9 to 9.5. The lowest 10% of all the best signal value was<3. Conclusion The waveform score is a new parameter indicating the reliability of each measurement signal. The best signal value indicates the best measurements of each session (Not the mean of the measurements). To date, our results show that the lower 10% percentile is <3. This could suggest that all the measurements with waveform score lower than 3 should be discarded.