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Can we treat glaucoma by non‐IOP related approaches?
Author(s) -
STALMANS I
Publication year - 2010
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2010.2153.x
Subject(s) - glaucoma , medicine , neuroprotection , intraocular pressure , ophthalmology , ocular hypertension , disease , risk factor , intensive care medicine
Intra‐ocular pressure is the main risk factor for the progression of glaucoma. However, intra‐ocular pressure lowering is not always sufficient to halt the progressive ganglion cell loss. Indeed, additional risk factors have been identified for glaucoma progression that can explain why some patients progress despite rigourous intra‐ocular pressure lowering. Vascular risk factors, such as low perfusion pressure, can be taken into account in the management of our glaucoma patients. The treatment options for these vascular risk factors will be discussed during the lecture. Moreover, neuroprotective strategies might open therapeutic perspectives to directly support the ganglion cells and thus help stabilizing the disease. Possible neuroprotective agents will be highlighted.