Pharmacological overview of the ophthalmic anaesthesia

Purpose Review of the chemical properties, differences between the effectiveness of the ophthalmological used local anaesthetics. Historical overview from 1860, year of the isolation of cocaine, to date. Methods Didactic and substantive summary of the literature. Results Specification of the basicity, lipophilicity, physicochemical properties, and the advantages, and disadvantages of adding adrenalin in different concentrations. Local anaesthetics also have adverse effects. All stimulate central nervous system, therefore it is very important to have a proper anamnesis, especially information about drug hypersensitivity from the patient. Conclusion Interventions must be carried out in the view of drug interactions, with personalized choice of drugs and dose.