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Acute retinal necrosis associated optic neuropathy
Author(s) -
Witmer Matthew T.,
Pavan Peter R.,
Fouraker Bradley D.,
LevyClarke Grace A.
Publication year - 2011
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2010.01911.x
Subject(s) - medicine , optic nerve , acute retinal necrosis , optic neuropathy , differential diagnosis , retinal , pathogenesis , retinal vasculitis , ophthalmology , vasculitis , pathology , ischemia , disease , retinitis , immunology , virus , human cytomegalovirus
Acute retinal necrosis (ARN) syndrome is characterized by severe intraocular inflammation, occlusive vasculopathy and peripheral retinal necrosis. Vision threatening complications of this syndrome include retinal detachment, macular oedema and ischaemia and optic neuropathy. Optic nerve involvement may be the presenting sign of ARN and this condition should be included in the differential diagnosis of acute papillitis. Several mechanisms may lead to ARN associated optic neuropathy including vasculitis, optic nerve ischaemia and direct optic nerve invasion by the herpes virus. We review optic nerve involvement during ARN and present its incidence, pathogenesis, differential diagnosis and treatment.