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Comparison of the peripapillary retinal nerve fiber layer thickness in healthy subjects measured by spectral‐domain Cirrus optical coherence tomography and time‐domain Stratus optical coherence tomography
Author(s) -
FUERTES I,
PINILLA I,
GARCIA MARTIN E,
GIL ARRIBAS L,
IDOIPE M,
CALVO PEREZ P
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.443.x
Subject(s) - optical coherence tomography , cirrus , nerve fiber layer , ophthalmology , retinal , medicine , reproducibility , fourier domain , tomography , glaucoma , quadrant (abdomen) , nuclear medicine , surgery , radiology , physics , mathematics , statistics , meteorology
Purpose to compare Cirrus Fourier‐domain optical coherence tomography (OCT) with Stratus Time‐domain OCT for measuring the peripapillary retinal nerve fiber layer (RNFL) thickness in healthy subjects. Methods One hundred and thirty two healthy subjects were prospectively and consecutively selected. Only one eye was ramdomly included in the study. All of them underwent three optic disc cube 200x200 scans with the Cirrus HD‐OCT system (Carl Zeiss Meditec, Inc.). The average of the 3 scans was calculated. With the Stratus OCT system (Carl Zeiss Meditec, Inc.) a fast RNFL thickness scan was recorded. The average of RNFL thickness, and RNFL thickness at each quadrant, and each 12 clock‐hours position was evaluated comparing both devices. Reproducibility of RNFL thickness measurements using de Cirrus HD‐OCT was studied, and the variation coefficient (COV) was calculated. Results Mean age was 40.06 ± 13.63 years (ranged from 17 to 72 years). Thirty nine were men (29.5%) and 93 women (70.5%). The average of the peripapillary RNFL thickness was 96.16 µm and 98.27 µm using Cirrus HD‐OCT and Stratus OCT respectively (p=0.001). Statistically differences were found in the temporal quadrant (p=0.026) as well as in several hour sectors. The Cirrus HD‐OCT reproducibility was high, with a mean COV of 4.54% (ranged from 1.64% to 6.37%). Conclusion Mean peripapillary RNFL thickness measured with Cirrus HD‐OCT is slightly lower than with Stratus OCT.