Premium
Differences in macular thickness studied by time domain optical coherence tomography (OCT) and spectral domain OCT in healthy subjects
Author(s) -
IDOIPE M,
GIL ARRIBAS L,
PINILLA I,
GARCIA MARTIN E,
FUERTES LAZARO M
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.441.x
Subject(s) - optical coherence tomography , ophthalmology , retinal , medicine , diabetic retinopathy , optics , optometry , physics , diabetes mellitus , endocrinology
Purpose To compare Stratus Time‐Domain optical coherence (OCT) with Spectralis Spectral‐domain OCT for measuring macular thickness in healthy patients. Methods Prospective study. Fifty‐ five healthy subjects were studied. All them undewent 3 Time Domain Optical Coherence Tomograph (OCT) scanning (Stratus OCT, Carl Zeiss Meditec, Inc.), fast macular thickness scan strategy, and 3 Spectral Domain OCT (Spectralis OCT; Heidelberg Engineering, Heidelberg, Germany) with macular scan 512 x 128 volume cube. Mean values of macular thickness measurement of the nine areas corresponding with “Early Treatment Diabetic Retinopathy Study” (ETDRS) were compared between both tomographs. Results We examined 55 healthy subjects, 43 women and 12 men, mean age was 35.64 ±13.73 years. Central thickness measured by Status OCT was 200.51 ± 17.98; central thickness obtained by Spectralis was 276.34 ± 20.71 microns. The t‐test assesses whether the means of all ETDRS macular areas measuremnts of the two tomographs are statistically different from each other, finding that Spectralis central thickness measuments was 75.83 microns higher than using the Stratus OCT. Conclusion Time Domain OCT uses the joint of the inner and outer segments of the photoreceptors as outer reference for macular thickness calculation whereas Spectral Domain OCT bases its reference in the retinal pigment epithelium, so differences between both of them are predictable. With our study we obtain a measurement of useful conversion to extrapolate the results obtained with a tomograph to the other one, being of great utility in the clinical practice.