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Comparison of corneal thickness, anterior segment depth and pupil diameter between patients with neovascular age‐related macular degeneration and controls
Author(s) -
PAHOR D,
KNEZ N,
SISKO K
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.430.x
Subject(s) - medicine , macular degeneration , ophthalmology , pupil , scheimpflug principle , significant difference , cornea , optics , physics
Purpose The goal of this study was firstly to compare corneal thickness at four different locations, anterior depth and pupil diameter between patients with neovascular age‐related macular degeneration and healthy individuals and secondly, to find out any possible anterior segment related risk factor for AMD development. Methods In this prospective study 69 patients (119 eyes) with neovascular age‐related macular degeneration with no history of any ocular disease or surgery were included. The 31 controls (56 eyes) were also enrolled. Informed consent was obtained from all recruited individuals. Each subject underwent complete ophthalmic examination. Galilei Dual Scheimpflug Analyzer (version 3.0, Ziemer Ophthalmic Systems AG, Switzerland), a non‐invasive diagnostic system designed for analysis of anterior chamber of the eye, was used for anterior segment evaluation. Results Comparison of corneal thickness at central, paracentral, peripheral zone and at the thinnest point revealed no statistically important difference between patients with age‐related macular degeneration and controls (P<0,5). There was a statistically significant difference in the mean anterior chamber depth between both groups (P=0,002). We did not observe statistically important difference in pupil diameter between both group (P>0,5). Conclusion The results of our study confirmed that the corneal thickness and pupil diameter are not associated with age‐related macular degeneration. Further investigations are necessary to confirm our results and to find out a possible role of anterior chamber depth as an additional risk factor for AMD development.