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Metastatic cancer presenting with ocular symptoms: a series of cases
Author(s) -
PEREZ GARCIA D,
TOBENA PUYAL M,
VALYI Z,
IBANEZ J,
ROJO ARNAO M,
JIMENEZ DEL RIO B,
CRISTOBAL JA,
FERRER A
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.354.x
Subject(s) - medicine , metastasis , cancer , adenocarcinoma , incidence (geometry) , uvea , lung cancer , metamorphopsia , disease , carcinoma , oncology , visual acuity , surgery , eye disease , physics , optics
Purpose Choroidal metastasis is the most frequent intraocular tumour. Lung cancer in men and breast cancer in women are the most common primary sources, followed by the digestive tract. The incidence of uveal metastasis is much higher after authopsy than in clinical series so its impact is underestimated. We present a series of cases of choroidal metastasis as the initial presentation of malignant disease. Methods We collected 5 patients in our hospital from August 2006 to April 2009 of choroidal metastasis as initial presentation of malignant disease. Primary sources, clinical and therapeutic management were analysed. Results 3 of the 5 patients were women (60%). Ophthalmological symptoms were decreased visual acuity in 2 patients (40%) and metamorphopsia in 3 (60%). As primary source were found lung cancer in 2 cases ( 1 adenocarcinoma and 1 oat cell carcinoma), pancreas adenocarcinoma in 2 cases and 1 unknown origin. Only one of the patients was considered candidate to receive brachytherapy. Conclusion Metastasis to the uvea is not a rare event due to the prolonged survival time of many cancer patients. Ophthalmologist should be aware of incidence, clinical features and management of choroidal metastasis as well as the prognosis for affected patients.