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Major eye diseases and risk factors associated with systemic hypertension in an adult chinese population: the Beijing Eye Study
Author(s) -
LIBONDI T,
JONAS JB,
WANG S,
XU L,
WONG TY,
CUI T,
LI Y,
YANG H,
CONG S
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.2447.x
Subject(s) - medicine , blood pressure , glaucoma , intraocular pressure , ophthalmology , ocular hypertension , eye examination , diabetic retinopathy , macular degeneration , hypertensive retinopathy , population , diabetes mellitus , cardiology , visual acuity , endocrinology , environmental health
Purpose To assess the relationship of hypertension with major eye diseases and other ocular parameters. Methods The Beijing Eye Study is a population‐based study. Examination at baseline in 2001; follow‐up examination in 2006; 3222 subjects had blood pressure measurements.All participants underwent a thourough ophthalmic examination and blood pressure measurement. Hypertension was defined as a systolic blood pressure ≥140 mm Hg and/or a diastolic blood pressure ≥90 mm Hg, and/or self‐reported current treatment for hypertension with antihypertensive medication. Results Mean age of participants in the present study was 60.4±10.0 years. Hypertension was present in 1500 (46.6%) of the 3222 subjects who had their blood pressure measured. In multiple regression analysis, hypertension was associated with higher intraocular pressure (P = 0.005), arterio‐venous nicking (P = 0.009),retinal vein occlusions (P = 0.02), and diabetic retinopathy (P = 0.02). Hypertension was not significantly associated with the prevalence of open‐angle glaucoma (P = 0.19) or angle‐closure glaucoma (P = 0.15), age‐related macular degeneration (P = 0.73), nuclear cataract (P = 0.88), posterior subcapsular cataract (P = 0.30), cortical cataract (P = 0.10), or area of alpha zone (P=0.05) or beta zone of parapapillary atrophy (P = 0.95). Conclusion In Chinese persons, while controlling for other systemic parameters, hypertension was associated with increased intraocular pressure, retinal microvascular abnormalities, and prevalence of retinal vein occlusion and diabetic retinopathy. Hypertension was not associated significantly with age‐related macular degeneration, age‐related cataract, or glaucoma