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Management of retinal tumours
Author(s) -
DESJARDINS L
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.1363.x
Subject(s) - retinoblastoma , medicine , cryotherapy , enucleation , fundus (uterus) , differential diagnosis , radiation therapy , coats' disease , strabismus , ophthalmology , radiology , surgery , retinal , pathology , biochemistry , chemistry , gene
Purpose To describe the clinical presentation, main diagnostic tools, differential diagnostic and managment of retinoblastoma. Methods Diagnostic modalities include fundus exam under general anesthesia with fundus pictures, ultrasonography and MRI. The more frequent differential diagnosis are coats disease and PHPV. Diffuse infiltrating retinoblastoma can be very difficult to identify An overview of the different therapeutic modalities of retinoblastoma with their specific indications and guidelines for follow up of patients and genetic counseling will be given. Results Unilateral massive retinoblastoma with no vision left is usually treated by enucleation while most bilateral retinoblastoma and 20% of unilateral can be treated by various conservative techniques including chemotherapy and chemothermotherapy, cryotherapy, plaque brachytherapy and external beam radiotherapy. Conclusion Early diagnosis of retinoblastoma is still the most important prognostic factor examination of the fundus is warranted in all children with leucokoria and/or strabismus.