Premium
What is the consequence of retinal detachment on anatomy and function?
Author(s) -
CREUZOT C
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.1341.x
Subject(s) - retinal detachment , retinal , retina , subclinical infection , medicine , ophthalmology , fibrosis , edema , epiretinal membrane , visual acuity , surgery , neuroscience , pathology , biology , vitrectomy
Purpose To present the structural and functional consequences on retina after retinal detachment Methods Author will show the consequences of experimental retinal detachment in animal models. These changes prevent retinal cells from a normal post‐operative functioning. However, these conditions have to be differentiated from post‐operative visual loss due to macular edema, long‐standing subretinal fluid, epiretinal membrane or macular hole formation. Results Retinal detachment leads to severe changes on retinal cells: outer segment shortening, fibrosis, glial proliferation. This situation is the target of neuroprotective treatment. By contrast, some situations where the bad recevoery is due to an associated disease (edema, membrane...) illustrated by clinical cases can need surgical treatment. Conclusion Bad functional recovery after retinal detachment can be explained by anatomic consequences on photoreceptors with subclinical fibrosis or some associated complications.