Premium
Clinical features and follow‐up results of pulsating polypoidal choroidal vasculopathy treated with photodynamic therapy
Author(s) -
Byeon Suk Ho,
Lew Young Ju,
Lee Sung Chul,
Kwon Oh Woong
Publication year - 2010
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2009.01517.x
Subject(s) - medicine , photodynamic therapy , ophthalmology , indocyanine green angiography , fluorescein angiography , ophthalmoscopy , presentation (obstetrics) , angiography , visual acuity , surgery , retinal , chemistry , organic chemistry
Acta Ophthalmol. 2010: 88: 660–668 Abstract. Purpose: To report on the clinical course of pulsating polypoidal choroidal vasculopathy (PCV) treated with photodynamic therapy (PDT). Methods: A total of 63 eyes of 58 consecutive patients diagnosed with PCV, treated with PDT and followed up for at least 6 months were enrolled. Best‐corrected visual acuity (BCVA), fluorescein angiography and high‐speed indocyanine green angiography (ICGA) using confocal scanning laser ophthalmoscopy (HRA) were performed. Results: Of the 63 PCV eyes, 14 eyes (22.2%) of 14 patients were classified as having pulsating PCV. The mean age of pulsating PCV patients was 60.6 ± 7.0 years (48–69 years), which was younger than non‐pulsating PCV patients (65.7 years, p = 0.035). The mean follow‐up period was 23.9 ± 10.7 months, and PDT was administered 1.6 ± 0.9 times to pulsating PCV patients. The mean logMAR BCVAs were 0.85 ± 0.47 at presentation and 0.71 ± 0.52 at final examination. Extensive haemorrhagic events were more common in pulsating than in non‐pulsating PCV patients (57.1% versus 26.5%, p = 0.032). However, the risk of haemorrhage within 3 months of PDT was similar for both pulsating PCV and the remaining patients (14.3% versus 20%, p = 0.723). Conclusion: Pulsating PCV showed distinctive features including a relatively younger patient age at presentation, and a haemorrhagic tendency (especially extensive). However, the use of PDT did not directly increase the risk of haemorrhage in pulsating PCV patients.