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Preliminary reading centre concordance in OCT grading in the UK IVAN Study
Author(s) -
PATTON WP,
MULDREW KA,
PETO T,
LENFESTY P,
HARDING SP,
CHAKRAVARTHY U
Publication year - 2008
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2008.629.x
Subject(s) - concordance , grading (engineering) , optical coherence tomography , medicine , retinal , optometry , ophthalmology , civil engineering , engineering
Purpose To report on concordance of optical coherence tomography (OCT) grading in the Network of Ophthalmic Reading Centres UK (NetwORC UK). The present study looks at concordance of OCT gradings across the network for patients enrolled in the UK IVAN Study. Methods A set of 5 patient scans (6 radial line scans and one 7mm offset scan using the Stratus OCT III (Zeiss, UK)) were graded by accredited graders at all three centres. Scans were exported as JPEG images with a corresponding PDF. Measurements for the Outer High Reflectivity Band (OHRB), Sub Retinal Fluid (SRF), Pigment Epithelial Detachment (PED), maximum height of largest cyst, maximum retinal thickenss (MRT) and foveal retinal thickness (FRT) were taken, if present. Results In all cases an acceptable level of concordance was achieved. One case proved more problematic than the others and results were more varied. For OHRB, SRF, PED, cyst, MRT and FRT the measurements by individual graders were consistent in 4 out of 5 cases. One case showed wider‐ranging measurements with the range for OHRB varying by 0.25mm (mean thickness 0.22mm). Conclusion The present study shows an acceptable level of concordance for OCT grading across NetwORC UK. In difficult cases, the complexity of AMD grading explained the lack of total concordance when an abnormal thickening of the OHRB is present. The most problematic case had an area of moderate hyperreflectivity anterior to the OHRB which caused difficulty and highlighted a specific area for further training and a protocol amendment. The exercise was useful in highlighting both individual and overall training needs which are currently being addressed in each of the RCs. The concordance study is being extended to include a larger dataset.