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Prevalence of optic disc drusen in an adult Chinese population: the Beijing Eye Study
Author(s) -
You Qi Sheng,
Xu Liang,
Wang Ya Xing,
Jonas Jost B.
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2008.01211.x
Subject(s) - beijing , drusen , optometry , chinese population , ophthalmology , medicine , population , china , macular degeneration , geography , biology , environmental health , genetics , gene , genotype , archaeology
. Purpose: This study aimed to determine the prevalence of optic disc drusen and their associations with ocular and general parameters. Methods: The Beijing Eye Study included 4439 of 5324 subjects invited to participate (response rate 83.4%). All subjects were aged ≥ 40 years. The present investigation involved 8594 (96.8%) eyes of 4324 (97.4%) subjects from whom readable fundus photographs of at least one eye were available. The main outcome parameter was the presence of optic disc drusen defined as round, whitish bodies. Results: Optic disc drusen were detected in nine (0.1 ± 0.05%) eyes of eight subjects (five women). The prevalence rate was 0.2 ± 0.07% (95% confidence interval 0.07−0.33%) per subject. Optic disc drusen were significantly associated with small optic discs (p < 0.001). They were not statistically associated with age (p = 0.90), gender (p = 0.73), intraocular pressure (p = 0.97), refractive error (p = 0.71), visual field defects (p = 0.47) or corrected visual acuity (p = 0.84). Conclusions: Optic disc drusen are present in about two in 1000 adult Chinese people in Northern China. The main associated factor is a small optic disc.