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Longitudinal study of anterior segment inflammation by ultrasound biomicroscopy in patients with acute anterior uveitis
Author(s) -
Peizeng Yang,
Qianli Meng,
Xiangkun Huang,
Hongyan Zhou,
Li Wang,
Kijlstra Aize
Publication year - 2009
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2008.01194.x
Subject(s) - ultrasound biomicroscopy , medicine , ciliary body , uveitis , ophthalmology , ultrasound , surgery , glaucoma , radiology
. Purpose: This study aimed to investigate dynamic changes in the anterior segment in patients with acute anterior uveitis (AAU) using ultrasound biomicroscopy (UBM). Methods: Acute anterior uveitis was diagnosed in 18 patients according to history and ocular examinations. Ultrasound biomicroscopy was performed and the results at three time‐points (within 2 weeks of the uveitis attack, and at 2−4 weeks and 6 weeks after it) were analysed. The relationships between clinical manifestations and UBM findings were also evaluated. Results: All investigated AAU patients showed severe ciliary injection, numerous dust keratic precipitates (KPs), aqueous flare and inflammatory cells, and were treated predominantly with corticosteroid and cycloplegic eyedrops. Ultrasound biomicroscopy showed a large number of cells in the anterior and posterior chamber, marked oedema and exudates in and around the iris and ciliary body within 2 weeks of AAU onset. These abnormalities were dramatically improved at 2−4 weeks and almost resolved at 6 weeks and thereafter. Conclusions: Ultrasound biomicroscopy reveals severe inflammatory changes in and around the ciliary body in patients with AAU. These signs rapidly resolve upon treatment.