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Histopathological findings in failed human epikeratophakia lenticules
Author(s) -
Wang Rong Guang,
Hjortdal Jesper Ø.,
Ehlers Niels,
Krogh Erik
Publication year - 1994
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1994.tb02774.x
Subject(s) - stroma , cornea , stromal cell , ophthalmology , epithelium , astigmatism , medicine , pathology , anatomy , optics , immunohistochemistry , physics
. Six human epikeratophakia lenticules were removed 1 to 23 months after refractive keratoplasty for aphakia (n = 2) and myopia (n = 4). The myopic group included one epi‐lenticule treated with ArF‐excimer laser for hyperopia. Reasons for removal were epithelial defect (n = 4), edema of host cornea (n = 1), and overcorrection (n = 1). The epi‐lenticule stroma showed centrally a regular fibrillar structure with a low keratocyte density. Electron microscopy (n = 1) revealed preserved cytoplasmic organelles and nuclear appearance. Mononuclear cells were absent. Polysaccharide was demonstrated in the stroma. Bowman's layer was normal without breaks. The epithelium had variable thickness. In the peripheral wound region stromal and epithelial irregularities were evident.