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C‐reactive protein serum levels in patients with ocular disease
Author(s) -
Tervo T.,
Setten G.B.,
Hovi M.,
Pakarinen M.,
Tarkkanen A.,
Valtonen V.
Publication year - 1994
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1994.tb02747.x
Subject(s) - c reactive protein , medicine , endophthalmitis , acute phase protein , keratitis , cellulitis , gastroenterology , uveitis , ophthalmology , surgery , inflammation
. Hepatocyte derived C‐reactive protein (CRP) is a sensitive indicator for inflammatory or infectious processes in a variety of tissues. As several other plasma proteins it is regarded as part of the acute phase response to a variety of tissue damage. CRP is commonly used in general medicin as a tool for the follow‐up of especially bacterial infections. However, it has not been widely used in ophthalmology. In the present study CRP values in serum samples from 51 patients with various acute ocular diseases were determined semiquantitatively. High CRP levels were found most frequently in patients with either preseptal cellulitis (83.3%) or endophthalmitis (25.8%) whereas in the serum of patients with keratitis and uveitis, CRP exceeded 20 mg/l in only 18.7% of the cases. In a control group of 10 patients with retinal detachment the mean CRP level was 2.3 mg/l ( sd ±0.98 mg/ml). The clinical significance and the prognostic value of CRP determinations during ocular diseases are discussed.