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Long‐term results with organ cultured, cryopreserved human corneal grafts. Re‐examination of 17 patients
Author(s) -
Erdmann Lotte,
Ehlers Niels
Publication year - 1993
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1993.tb04666.x
Subject(s) - cryopreservation , term (time) , medicine , ophthalmology , corneal transplantation , corneal transplant , cornea , surgery , biology , microbiology and biotechnology , embryo , physics , quantum mechanics
. Seventeen organ cultured cryopreserved corneas were grafted in 1978–79. When published in 1982, 12 of the grafts (71%) were clear with an average thickness of 0.51 mm and an endothelial density of 1028 cells/mm 2 . A re‐examination of these patients after 13 years is presented. Seven grafts (58%) were clear. Average CCT was 0.51 mm and endothelial cell density was 988 cells/mm 2 . Visual acuity was 0.4 or better. The morphology resembled that seen after 1 year with large, multinucleated cells. It is concluded that cryopreserved grafts show a fair long‐term survival. Cryopreservation may still present a possibility in the establishment of a corneal bank with the perspective of supplying histocompatible donor material.