Premium
Prevention of the rise in intraocular pressure following neodymium‐YAG posterior capsulotomy using topical clonidine
Author(s) -
Loewenstein Anat,
Varssano David,
Lazar Moshe,
Geyer Orna
Publication year - 1991
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1991.tb02023.x
Subject(s) - clonidine , intraocular pressure , medicine , saline , capsulotomy , ophthalmology , anesthesia , posterior capsulotomy , intraocular lens
We studied the ability of topical clonidine, an alpha‐agonist, to suppress the acute rise in intraocular pressure (IOP) following neodymium‐YAG posterior capsulotomy (YPC). In a randomized controlled trial 63 eyes were pretreated with one drop of either 0.25% clonidine or saline 1 h before performing YPC and immediately following the procedure. The greatest IOP rise in the saline treated eyes occurred in the second hour after YPC, when the mean (± sd ) IOP rose from a baseline pressure of 12.7 ± 3.2 to 18.7 ± 10.7 mmHg. In clonidine treated eyes, the IOP fell from a mean of 11.9 ± 3.4 to 9 ± 3.3 mmHg 2 h postoperatively. In the saline treated group 9 eyes (27%) developed an IOP rise greater than 10 mmHg. Clonidine proved to be highly effective in preventing the rise in IOP following YPC.