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Evaluation of the retinal nerve fiber layer in early glaucoma. Physiological and pathological findings
Author(s) -
Baun Ole,
Møller Bent,
Kessing Svend V.
Publication year - 1990
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1990.tb01691.x
Subject(s) - nerve fiber layer , retinal , glaucoma , pathological , ophthalmology , medicine , neuroscience , optometry , psychology , pathology
. In this study on retinal nerve fiber layer (RNFL) evaluation in early glaucoma we investigated whether the greatest retinal vein width is a usable measure to distinguish physiological findings from beginning pathological defects. Seven normal control eyes and 23 glaucomatous eyes with small relative Octopus defects (>10 db and <20 db) were photographed. In the control group 3 eyes had no RNFL loss, 4 eyes had localized defect <1 vein width. In the glaucoma group 1 eye had a localized defect <1 vein width, 7 eyes had localized defects ≥1 vein width and 12 eyes had diffuse defects. Based on the present study it seems reasonable to define small localized defects as pathological if they at any point are >1 vein width. According to this definition our study showed a specificity of 100% and sensitivity of 95% which means that the method is usable as an extra parameter in the diagnosis of early glaucoma.