Premium
Colour vision in a family with Sorsby's dystrophy
Author(s) -
Atchison David A.
Publication year - 1989
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1989.tb04393.x
Subject(s) - dystrophy , medicine , optometry , macular dystrophy , family history , psychology , ophthalmology , retinal , pathology , surgery
Fraser & Wallace (1971) investigated a family with Sorsby's dystrophy, and found a high prevalence of a mild red‐green colour deficiency. Using a battery of tests, I re‐examined the colour vision of members of the family at risk of developing the disease. I conclude that the mild colour vision defect is classical sex linked recessive deuteranomaly occurring adventiously in the family; its high prevalence is due to its being introduced by at least 3 persons marrying into the family. Two alternative hypotheses of the colour vision deficiency are that it is an acquired disorder which is a prodromal sign of the dystrophy or that it is inherited in an autosomal dominant manner. However, these hypotheses were rejected because the colour vision deficiency had the characteristics of a typical sex linked disorder. These findings emphasise that it is important to exclude any co‐existing inherited colour vision defect when defining the clinical features of any retinal dystrophy by careful evaluation of unaffected family members.