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Uncomplicated retrobulbar neuritis and the development of multiple sclerosis
Author(s) -
Anmarkrud Nils,
Slettnes Olav N.
Publication year - 1989
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1989.tb01876.x
Subject(s) - multiple sclerosis , medicine , neuritis , cerebrospinal fluid , optic neuritis , retrospective cohort study , surgery , psychiatry
A retrospective study of 30 patients hospitalized with a diagnosis of uncomplicated retrobulbar neuritis was carried out. The follow‐up period was 2–11 years; 57% developed multiple sclerosis. When the initial examination revealed oligoclonal bands in the cerebrospinal fluid, the risk of developing multiple sclerosis increased to 79%. With normal cerebrospinal fluid the risk decreased to only 10%. In the majority of cases, the diagnosis of MS was made during the first 3 years after retrobulbar neuritis.