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Treatment versus no treatment in chronic open angle glaucoma
Author(s) -
Holmin Catharina,
Thorburn W.,
Krakau C. E. T.
Publication year - 1988
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1988.tb04006.x
Subject(s) - open angle glaucoma , glaucoma , medicine , ophthalmology , optometry
. In a controlled randomized study 15 patients (20 eyes) with chronic open angle glaucoma and visual field defects were followed for > 1 year, 12 of them were followed for 3 years. Half of the group were untreated controls, the other half treated with pressure reducing medical therapy. At least 5 consecutive computerized visual fields were recorded (COMPETER) on each eye, and the linear regression coefficient was calculated. With the reservation for uncontrolled compliance no significant difference in the line of favourable effect of pressure reduction could be spotted, in spite of an average pressure reduction in the treated group of 4 mmHg. More important than this result, which is open to criticism for the smallness of the material, uncontrolled compliance etc, is the lesson that a randomized experiment with treated and non‐treated glaucoma cases carried out in accordance with the Helsingfors convention is hardly feasible.