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Timolol/pilocarpine combination eye drops in open angle glaucoma and in ocular hypertension
Author(s) -
Høvding Gunnar,
Aasved Henry
Publication year - 1987
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1987.tb07048.x
Subject(s) - pilocarpine , timolol , miosis , ophthalmology , glaucoma , medicine , ocular hypertension , intraocular pressure , eye drop , open angle glaucoma , anesthesia , psychiatry , epilepsy
The effect of a newly developed ophthalmic solution containing both 0.5% timolol and 2% resp. 4% pilocarpine was compared with that of timolol 0.5% eye drops alone in 93 patients with manifest simple or capsular glaucoma or ocular hypertension. The medications were administered twice daily. The absolute additive effect of pilocarpine was small, although the combined solutions caused a statistically significantly greater reduction of the intraocular pressure than that achieved by timolol alone. This additional effect appeared to last at least 12 h. The effect of the test solutions containing 2% resp. 4% pilocarpine was very similar. Apart from the well‐known effects of the pilo‐carpine‐induced miosis, the combined test medications were generally well tolerated.