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Human Epidermal Growth Factor—the influence on the healing of surgically closed corneal wounds
Author(s) -
Calel Bertil,
Fagerholm Per
Publication year - 1987
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1987.tb02592.x
Subject(s) - medicine , wound healing , epidermal growth factor , ultimate tensile strength , cornea , significant difference , steroid , ophthalmology , surgery , materials science , receptor , hormone , metallurgy
The influence of topically applied human EGF on corneal wound healing was evaluated in surgically closed corneal wounds. In one group the corneal wound tensile strength was assesed after one week. No significant difference was found compared control. In another group, treated for 4 weeks, both eyes received steroids topically and one eye was treated with EGF. The tensile strength of the EGF treated wounds were significantly increased compared to control. The tensile strength after 4 weeks using steroids had not increased compared to the non steroid treated group after 1 week.