Premium
Effect of honan intraocular pressure reducer on ocular and optic nerve blood flow in phakic rabbit eyes
Author(s) -
Jay W. M.,
Aziz M. Z.,
Green K.
Publication year - 1986
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1986.tb06871.x
Subject(s) - reducer , intraocular pressure , blood flow , ophthalmology , medicine , anesthesia , optic nerve , blood pressure , rabbit (cipher) , elevated intraocular pressure , statistics , civil engineering , mathematics , engineering
The Honan Intraocular Pressure Reducer (HIPR) was applied to rabbit eyes for 30 min at pressure settings of 0, 30, 50, or 100 mmHg. Ocular blood flow was measured using ( 85 Sr) radioactively labelled 15 urn microspheres either with the HIPR applied to the eye or 15 min after removal. Intraocular pressure was measured before applying the HIPR, immediately after removal, or 15 min after removal. At all pressure settings, the HIPR significantly lowered the IOP ( P 0.05) both immediately and 15 min after removal. At all pressure settings, except 0 mmHg, blood flow was significantly ( P 0.05) both immediately and 15 min after removal. Al all pressure settings, except 0 mmHg, blood flow was significantly ( P 0.05) lower with the HIPR applied compared to 15 min after removal.