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Senile cataract and ascorbic acid loading
Author(s) -
Ringvold Amund,
Johnsen Harald,
Blika Sigmund
Publication year - 1985
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1985.tb06805.x
Subject(s) - ascorbic acid , aqueous humour , aqueous humor , chemistry , aqueous solution , ophthalmology , medicine , glaucoma , senile cataract , chromatography , organic chemistry , food science
Serum, aqueous humour, and lens ascorbic acid levels were determined by high‐performance liquid chromatography in cataract‐, closed‐angle glaucoma‐, and aphakic patients. The total number of 108 patients were subdivided into different groups. In several groups the pre‐operative serum and aqueous amounts were tested, whereafter patients in some groups were loaded with ascorbic acid orally. Finally, a second test was performed on samples taken during operation. It turned out that the ascorbic acid concentration mechanism in cataractous eyes needed more than 12 h for maximum reaction on the loading stimulus. The slow reaction is surprising compared to other species, and it may reflect an affection of the secretory process itself in this disease.