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Prevalence of retinopathy in diabetes treated with oral antihyperglycaemic agents
Author(s) -
Jerneld Bengt,
Algvere Peep
Publication year - 1985
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1985.tb05241.x
Subject(s) - medicine , logistic regression , diabetes mellitus , retinopathy , body mass index , correlation , diabetic retinopathy , gastroenterology , endocrinology , geometry , mathematics
. In a random sample of all diabetics treated with oral antihyperglycaemic agents on the island of Gotland, Sweden, retinopathy (Rp) was present in 24 (17%) of 140 patients examined. Eighteen patients had background Rp, 7 of these with exudative lesions. Four patients had pre‐proliferative and 2 proliferative Rp. On multiple logistic regression analysis a significant correlation was found between Rp on the one hand and a longer duration and a younger age at onset of the diabetes, on the other. Rp was also significantly correlated to higher levels of glycosylated haemoglobin (HbA1C). In an additional analysis restricted to the group with Rp, higher levels of HbA1C were found in persons with Rp of a more severe degree. On a simple logistic regression analysis, a significant correlation ( P < 0.05) was found between a high body mass index and a low prevalence of Rp, on multiple regression analysis this correlation became weaker ( P = 0.06).