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The normal fundus fluorescein angiogram IV
Author(s) -
Nielsen Niels Vesti
Publication year - 1985
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1985.tb01564.x
Subject(s) - fundus (uterus) , fluorescein , medicine , ophthalmology , percentile , posterior pole , visual acuity , mathematics , optics , physics , statistics , fluorescence
. A comparison of fundus elements in the posterior pole of the eye in a group of 48 clinically healthy subjects and in a group of 17 insulin dependent diabetics showed a significant overrepresentation ( P < 0.05) of hyperfluorescent and hypofluorescent elements among the diabetics, as estimated from serial fundus fluorescein angiograms at 3 examinations during one year. In the diabetics a significant intraindividual variation of hyperfluorescent elements (6/17 eyes) occurred during one year in contrast to the clinically healthy subjects (0/48)–( P < 0.01). The normal fundus fluorescein angiogram (i.e. in clinically healthy subjects) is characterized by: 1) a wide physiologic variation of the number of hyperfluorescent elements i.e. 0–4 elements or 0–11 elements as assessed with and without a one tailed 10% percentile as an upper limit. 2) Hypofluorescent elements in variable number may occur in 21% (upper limit 10% percentile) or 31% (without an upper limit) of normal eyes. 3) No intra‐individual variation of these hyper‐ and hypofluorescent elements developed during the observation period.