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Timolol in aqueous humour after topical administration
Author(s) -
Marén N.,
Calissendorff B. M.
Publication year - 1985
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1985.tb01555.x
Subject(s) - timolol , aqueous humour , eye drop , medicine , chemistry , anesthesia , aqueous humor , ophthalmology , plasma concentration , pharmacology , glaucoma
. The concentration of timolol in aqueous humour after one single drop of timolol ophthalmic solution was studied in 19 patients. Relatively high concentrations were found (mean: 626 ng/ml), but the individual differences were great (range: 0 ng/ml – 2080 ng/ml). Possible explanations are discussed. No detectable levels of timolol were found in plasma (detection level ≥ 1 ng/ml).