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Timolol and aceclidine
Author(s) -
Pol B. A. E.,
Wattel E.
Publication year - 1985
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1985.tb01554.x
Subject(s) - timolol , pilocarpine , medicine , intraocular pressure , glaucoma , ophthalmology , drug , anesthesia , pharmacology , epilepsy , psychiatry
. In the Netherlands timolol maleate, probably the drug of first choice in antiglaucoma therapy, is often combined with other intraocular pressure lowering drugs. The efficacy of most combinations have been discussed in the literature several times, except the one with aceclidine, a parasympathic drug, that has a reasonable popularity in Western Europe. Unlike pilocarpine, aceclidine does not seem to give a clinically significant additional pressure lowering effect in timolol pre‐treated eyes. The decrease in IOP in aceclidine pre‐treated eyes after single dose timolol seems to be an effect of timolol alone. Our results suggest that co‐administration of timolol and aceclidine is not a rational action in antiglaucomatous therapy.