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LYSOZYME CONCENTRATION IN TEARS‐ASSESSMENT OF REFERENCE VALUES IN NORMAL SUBJECTS
Author(s) -
AINE ESKO,
MÖRSKY PERTTI
Publication year - 1984
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1984.tb08445.x
Subject(s) - lysozyme , tears , reference values , standard deviation , age groups , reference range , logarithm , significant difference , medicine , normal values , zoology , chemistry , mathematics , surgery , demography , biology , statistics , biochemistry , mathematical analysis , sociology
The lysozyme content of tears in 126 healthy persons (249 samples) was studied by an initial rate immunoturbidimetric method. The lysozyme values kept a logarithmic distribution with logarithmic mean 1568 mg/l and median 1530 mg/l. The arithmetic mean with standard deviation was 1678 ± 633 mg/l. Lower lysozyme concentrations were observed in elderly people and children than in adults, but the concentration distributions in different age groups overlapped considerably. Statistically, the difference between the age groups ≥ 60 years and over 60 years was almost significant ( P = 0.012). No significant differences occurred between the sexes. Values within ± 2 sn from the logarithmic mean were included in the reference material. For 10–60‐year‐old persons, the reference range is 750–3300 mg/l and over 60 years old 650–2900 mg/l.