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DIABETIC RETINOPATHY II
Author(s) -
NIELSEN NIELS VESTI
Publication year - 1984
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1984.tb08403.x
Subject(s) - medicine , retinopathy , diabetic retinopathy , incidence (geometry) , blindness , diabetes mellitus , epidemiology , cohort , ophthalmology , pediatrics , endocrinology , optometry , physics , optics
The course of diabetic retinopathy was investigated in 273 out of 306 diabetics treated with oral hypoglycaemic agents (OHA) and 60 out of 72 diet‐treated diabetics in an epidemiological cohort study in a period of one year. In the OHA‐treated diabetics the allover prevalence of retinopathy did not change (P > 0.10) after one year (125/306 = 40.9% vs 122/273 = 44.7%). The one year incidence of new and deteriorated background was 3.7% and 6.6%, respectively. New cases of proliferative retinopathy developed in 1.1% and a worsening of pre‐existing proliferative retinopathy in 1.8%. Among diabetics with pre‐existing background retinopathy (n = 93) 14% progressed, and 2% became proliferative. A worsening of retinopathy occurred more frequently (P < 0.01) in diabetics with an onset age < 60 years and with a duration > 5 years. The incidence of partial sight and legal blindness due to retinopathy was 2.2% and 1.9%, respectively, among all diabetics. Among diet‐treated diabetics, 2 diabetics (3.3%) developed background retinopathy. None with preexisting background retinopathy showed any deterioration.