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LOCAL APPLICATION OF INDOMETHACIN IN HEALTHY EYES AND IN POST‐OPERATIVE CATARACT PATIENTS
Author(s) -
KROGH E.,
HENNING V.,
GLUUD B.
Publication year - 1984
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1984.tb06762.x
Subject(s) - medicine , ophthalmology , optometry
The effects of locally applied Indomethacin were studied. Ten healthy subjects received 1 drop of a 1% watery solution 4 times a day in their left eye during 2 weeks, the right eye serving as control. Neither changes in visual acuity and refraction nor in the appearance and function of the external and anterior segment of the eye were found during this period. Sixty‐four patients underwent surgery for simple senile cataract. Half of the patients, by random selection, received Indomethacin solution locally during the first week. The remaining half received routine treatment with a compound preparation of antibiotics and corticosteroid from the third post‐operative day. An inflammatory score was calculated and was found to be significantly reduced in the Indomethacin group during the first week.